Chloramphenicol+dexamethasone+polymyxin B
About Chloramphenicol+dexamethasone+polymyxin B
Chloramphenicol+dexamethasone+polymyxin B belongs to the class of combination medications called ‘antibiotics' and 'steroids' used for the treatment of bacterial eye infections and ear infections. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Chloramphenicol+dexamethasone+polymyxin B does not work against infections caused by viruses and fungi.
Chloramphenicol+dexamethasone+polymyxin B is a combination of Chloramphenicol, Dexamethasone, and Polymyxin B. Chloramphenicol is an antibiotic that acts by interfering with the formation of essential proteins required for bacterial growth. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation. Polymyxin B is bactericidal, which works by killing the bacterial cell and preventing the formation of bacterial cell walls, which is essential for survival. Together Chloramphenicol+dexamethasone+polymyxin B prevent the spread of eye and ear infections caused by a wide range of gram-negative bacteria causing eye/ear infections.
You should use this medicine as prescribed by your doctor. When used in the eyes, the common side effects are eye discomfort, eye irritation, and a burning sensation in the eye. When used as ear drops, the side effects include mild irritation and temporary ear discomfort. Most of these side effects of Chloramphenicol+dexamethasone+polymyxin B do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to Chloramphenicol+dexamethasone+polymyxin B or any other medicines, please tell your doctor. Chloramphenicol+dexamethasone+polymyxin B should be used with caution in children. You are advised to consult a doctor if you are pregnant or breastfeeding. You are recommended not to use contact lenses during the course of Chloramphenicol+dexamethasone+polymyxin B as it may worsen the infection. You are advised to maintain a 10-minute time gap between using Chloramphenicol+dexamethasone+polymyxin B and other eye drops. Please do not touch the container tip to the eye, eyelids, or surrounding areas as it may contaminate Chloramphenicol+dexamethasone+polymyxin B and cause eye infections. Before using Chloramphenicol+dexamethasone+polymyxin B, inform your doctor if you have fungal infections, viral infections such as herpes simplex or varicella, or parasitic infections such as amoebiasis. Do not use Chloramphenicol+dexamethasone+polymyxin B if you have tuberculosis, damaged cornea, ulceration, lesions with missing skin that cover the eye or ear, and increased pressure inside the eye.
Uses of Chloramphenicol+dexamethasone+polymyxin B
Medicinal Benefits
Chloramphenicol+dexamethasone+polymyxin B is a combination of Chloramphenicol, Dexamethasone, and Polymyxin B belongs to the class of combination medications called ‘antibiotics' and 'steroids' used for the treatment of bacterial eye infections and ear infections. Chloramphenicol is an antibiotic that acts by interfering with the formation of essential proteins required for bacterial growth. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation. Polymyxin B is bactericidal, killing the bacterial cell by preventing bacterial cell walls' formation essential for survival. Together Chloramphenicol+dexamethasone+polymyxin B prevent the spread of eye and ear infections caused by a wide range of gram-negative bacteria causing eye/ear infections.
Directions for Use
Storage
Side Effects of Chloramphenicol+dexamethasone+polymyxin B
Eye drops:
- Eye discomfort
- Eye irritation
- Burning sensation in the eye
Ear drops:
- Mild irritation
- Temporary ear discomfort
Drug Warnings
Please tell your doctor if you are allergic to Chloramphenicol+dexamethasone+polymyxin B or any other medicines. Chloramphenicol+dexamethasone+polymyxin B should be used with caution in children. You are advised to consult a doctor if you are pregnant or breastfeeding. You are recommended not to use contact lenses during the course of Chloramphenicol+dexamethasone+polymyxin B as it may worsen the infection. You are advised to maintain a 10-minute time gap between using Chloramphenicol+dexamethasone+polymyxin B and other eye drops. Please do not touch the container tip to the eye, eyelids or surrounding areas as it may contaminate Chloramphenicol+dexamethasone+polymyxin B and cause eye infections. Before using Chloramphenicol+dexamethasone+polymyxin B, inform your doctor if you have fungal infections, viral infections such as herpes simplex or varicella, or parasitic infections such as amoebiasis. Do not use Chloramphenicol+dexamethasone+polymyxin B if you have tuberculosis, damaged cornea, ulceration, lesions with missing skin that cover the eye or ear and increased pressure inside the eye.
Drug Interactions
Drug-Drug Interactions: Chloramphenicol+dexamethasone+polymyxin B may interact with an anti-cancer agent (methotrexate), immune suppressant (azathioprine), antiviral drug (ritonavir), and a medication used to treat HIV (cobicistat).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Chloramphenicol+dexamethasone+polymyxin B should not be used in patients with fungal infections, viral infections such as herpes simplex or varicella, or parasitic infections such as amoebiasis, tuberculosis, damaged cornea, ulceration, and glaucoma (increased pressure inside the eye).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol may affect your ability to fight infections. So, it is recommended to avoid alcohol consumption until your condition improves.
Pregnancy
unsafeThe consequences of Chloramphenicol+dexamethasone+polymyxin B during pregnancy are unknown; therefore, do not use it unless your doctor deems it necessary. Ask your doctor for advice before using this medication if you are pregnant, suspect you may be pregnant or are planning a pregnancy.
Breast Feeding
cautionThe consequences of Chloramphenicol+dexamethasone+polymyxin B during breastfeeding are unknown; therefore, do not use it unless your doctor deems it necessary. Ask your doctor for advice before using this medication if you are breastfeeding.
Driving
cautionChloramphenicol+dexamethasone+polymyxin B may affect your vision. So, do not drive or operate heavy machinery until your vision clears after using Chloramphenicol+dexamethasone+polymyxin B.
Liver
safe if prescribedChloramphenicol+dexamethasone+polymyxin B can be used to treat eye/ear infections in patients with liver diseases.
Kidney
safe if prescribedChloramphenicol+dexamethasone+polymyxin B can be used for treating eye/ear infections in patients with kidney problems.
Children
safe if prescribedChloramphenicol+dexamethasone+polymyxin B can be used with caution in children to treat middle and outer ear infections. Use it only if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Sleep for at least six to eight hours to rejuvenate your eyes naturally.
- Wash your eyes with clean water at least two to three times a day
- Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.
- Keep your ear clean and dry.
- Avoid alcoholic beverages as they can make you dehydrated and affect your sleep. This effect can also affect your body’s ability to fight off infections.
Special Advise
- Do not wear contact lenses while using Chloramphenicol+dexamethasone+polymyxin B eye drops.
- Avoid getting water in your ears while bathing, showering, or swimming while treating an ear infection.
- Avoid prolonged exposure to sunlight while using Chloramphenicol+dexamethasone+polymyxin B as it may cause increased photosensitivity (sensitivity to light).
Patients Concern
Disease/Condition Glossary
Conjunctivitis: The inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid. It is a highly contagious infection that is spread by secretions of the eye. Symptoms include redness, itch, and discharge or crusting around the eye.
Bacterial ear infection: The outer, middle, and inner regions of the ear are all affected when a bacterium invades the ear, which causes bacterial ear infection. Due to inflammation and fluid buildup in the middle ear, ear infections can be uncomfortable. Short-term to long-term ear infections can be acute or chronic in nature. The term 'middle ear infection' also applies to otitis media.
FAQs
Chloramphenicol+dexamethasone+polymyxin B is used to treat bacterial eye and ear infections.
Chloramphenicol+dexamethasone+polymyxin B is a combination of three medicines: Chloramphenicol, Dexamethasone and Polymyxin B. Chloramphenicol is an antibiotic that acts by interfering with the formation of essential proteins required for bacterial growth. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation. Polymyxin B is bactericidal and works by killing the bacterial cell by preventing bacterial cell wall formation, which is essential for survival. Together Chloramphenicol+dexamethasone+polymyxin B prevent the spread of eye and ear infections caused by a wide range of gram-negative bacteria causing eye/ear infections.
It is not recommended that you wear contact lenses during the entire course of Chloramphenicol+dexamethasone+polymyxin B as they may worsen the infection. Therefore, you are advised to remove contact lenses before using Chloramphenicol+dexamethasone+polymyxin B and reinsert them after 24 hours of finishing the course of Chloramphenicol+dexamethasone+polymyxin B.
You are recommended to maintain a minimum of 10 minutes time gap between using Chloramphenicol+dexamethasone+polymyxin B and other eye drops and administering eye ointments in the last.
No, do not stop using Chloramphenicol+dexamethasone+polymyxin B, even after your symptoms are relieved. Stopping soon without completing your prescribed duration can lead to incomplete recovery and the return of symptoms or may lead to side effects. Instead, report your progress to your doctor and follow their advice. They will guide you on how to stop using Chloramphenicol+dexamethasone+polymyxin B safely without causing any side effects.
Store Chloramphenicol+dexamethasone+polymyxin B in its original container in a cool and dry place away from sunlight. Keep it out of the reach of children. Regularly check the expiration date on the label. When you need to dispose of the medicine, remove the label, place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink.
Lie down and tilt your head backward. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor or Squeeze a tiny amount of the cream/ointment/gel into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
If you apply too much Chloramphenicol+dexamethasone+polymyxin B wipe off the excess, with a clean cloth and wash the area with mild soap and water. Contact your doctor if you monitor any signs of irritation or allergic reactions.
The common side effects of Chloramphenicol+dexamethasone+polymyxin B that may be caused in some individuals such as burning sensation, itchiness, irritation, and dryness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
